cliot (version 1.0.0)

clif_c_aclf_score: CLIF-C ACLF Score for Acute-on-Chronic Liver Failure

Description

Calculates the CLIF-C ACLF (Consortium on Chronic Liver Failure - Acute-on-Chronic Liver Failure) score. This prognostic score is specifically designed for patients with ACLF (Acute-on-Chronic Liver Failure) to predict 28-day and 90-day mortality. It incorporates the CLIF-OF (Organ Failure) score, Age, and White Blood Cell count.

Usage

clif_c_aclf_score(age, wbc_count, bilirubin, creatinine, inr, map,
                  use_vasopressors, pao2_fio2_ratio, he_grade,
                  bilirubin_units = "mg/dL", creatinine_units = "mg/dL")

Value

A list containing:

CLIF_C_ACLF_Score

The calculated prognostic score.

CLIF_OF_Score

The intermediate Organ Failure score (Sum of 6 organ system scores).

Est_28_Day_Mortality

Estimated 28-day mortality probability.

Est_90_Day_Mortality

Estimated 90-day mortality probability.

Arguments

age

Numeric. Patient age in years.

wbc_count

Numeric. White Blood Cell count in x10^9/L.

bilirubin

Numeric. Total Bilirubin level.

creatinine

Numeric. Serum Creatinine level.

inr

Numeric. International Normalized Ratio.

map

Numeric. Mean Arterial Pressure in mmHg.

use_vasopressors

Numeric (0 or 1). Is the patient on vasopressors? (1 = Yes).

pao2_fio2_ratio

Numeric. PaO2/FiO2 ratio.

he_grade

Numeric (0-4). West Haven Grade of Hepatic Encephalopathy.

bilirubin_units

String. Units for bilirubin. "mg/dL" (default) or "umol/L".

creatinine_units

String. Units for creatinine. "mg/dL" (default) or "umol/L".

References

Jalan R, Saliba F, Pavesi M, et al. Development and validation of a prognostic score to predict mortality in patients with acute-on-chronic liver failure. J Hepatol. 2014;61(5):1038-1047. doi:10.1016/j.jhep.2014.06.012

Examples

# Example 1: High Mortality
# Age 60, WBC 15, Bili 15, Cr 4.0, INR 3.0, Pressors Yes, PF 150, HE Grade 3
clif_c_aclf_score(60, 15, 15, 4.0, 3.0, 60, 1, 150, 3)

# Example 2: Lower Mortality
# Age 45, WBC 8, Bili 5, Cr 1.5, INR 1.5, MAP 80, No Pressors, PF 350, HE Grade 1
clif_c_aclf_score(45, 8, 5, 1.5, 1.5, 80, 0, 350, 1)