cliot (version 1.0.0)

cockcroft_gault_crcl: Creatinine Clearance (Cockcroft-Gault Equation)

Description

Calculates Creatinine Clearance (CrCl) using the Cockcroft-Gault equation. This implementation replicates the MDCalc logic for weight selection: - BMI < 18.5: Uses Actual Body Weight. - BMI 18.5 - 24.9: Uses Ideal Body Weight. - BMI >= 25: Uses Adjusted Body Weight. If height is not provided, it defaults to using Actual Body Weight.

Usage

cockcroft_gault_crcl(sex, age, creatinine, weight_kg, height_cm = NULL,
                     creatinine_units = "mg/dL")

Value

A list containing:

CrCl_mL_min

The estimated Creatinine Clearance.

Weight_Used_kg

The specific weight value used in the calculation.

Method

Description of which weight formula was selected (Actual, Ideal, or Adjusted).

Arguments

sex

String. Patient sex ("Male" or "Female").

age

Numeric. Patient age in years.

creatinine

Numeric. Serum creatinine level.

weight_kg

Numeric. Actual body weight in kilograms.

height_cm

Numeric (Optional). Height in centimeters. Required to calculate BMI/IBW for the specific weight selection logic.

creatinine_units

String. Units for creatinine. Options: "mg/dL" (default) or "micromol/L".

References

Cockcroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Nephron. 1976;16(1):31-41. doi:10.1159/000180580 Winter MA, Guhr KN, Berg GM. Impact of various body weights and serum creatinine concentrations on the bias and accuracy of the Cockcroft-Gault equation. Pharmacotherapy. 2012;32(7):604-612.

Examples

# Example 1: Normal Weight Male
# Age 54, Cr 1.2, Wt 75kg, Ht 180cm (BMI ~23 -> Uses IBW)
cockcroft_gault_crcl("male", 54, 1.2, 75, 180)

# Example 2: Obese Female
# Age 65, Cr 0.9, Wt 90kg, Ht 160cm (BMI ~35 -> Uses Adjusted BW)
cockcroft_gault_crcl("female", 65, 0.9, 90, 160)

# Example 3: No Height Provided (Defaults to Actual Weight)
cockcroft_gault_crcl("male", 40, 1.0, 80)