cliot (version 1.0.0)

crusade_bleeding_score: CRUSADE Score for Post-MI Bleeding Risk

Description

Calculates the CRUSADE Bleeding Score to stratify the risk of in-hospital major bleeding in patients with NSTEMI (Non-ST-Elevation Myocardial Infarction). The score helps guide the choice and dosing of antithrombotic therapies to balance ischemic benefit against bleeding risk.

Usage

crusade_bleeding_score(hematocrit_percent, creatinine_clearance, heart_rate,
                       sex, chf_signs, prior_vascular_disease, diabetes,
                       systolic_bp)

Value

A list containing:

CRUSADE_Score

The calculated total score (Range 0-96).

Risk_Category

Classification (Very Low, Low, Moderate, High, Very High).

In_Hospital_Major_Bleeding_Risk

Estimated percentage probability of major bleeding.

Arguments

hematocrit_percent

Numeric. Baseline hematocrit level (%). <31: +9 pts. 31-33.9: +7 pts. 34-36.9: +3 pts. 37-39.9: +2 pts. >=40: 0 pts.

creatinine_clearance

Numeric. Creatinine clearance in mL/min (typically calculated via Cockcroft-Gault). <=15: +39 pts. >15-30: +35 pts. >30-60: +28 pts. >60-90: +17 pts. >90-120: +7 pts. >120: 0 pts.

heart_rate

Numeric. Heart rate at presentation (bpm). <=70: 0 pts. 71-80: +1 pt. 81-90: +3 pts. 91-100: +6 pts. 101-110: +8 pts. 111-120: +10 pts. >=121: +11 pts.

sex

String. "Male" (0 pts) or "Female" (+8 pts).

chf_signs

Numeric (0 or 1). Signs of Congestive Heart Failure at presentation. (1 = Yes, +7 pts).

prior_vascular_disease

Numeric (0 or 1). History of prior vascular disease (e.g., PAD, Stroke). (1 = Yes, +6 pts).

diabetes

Numeric (0 or 1). History of Diabetes Mellitus. (1 = Yes, +6 pts).

systolic_bp

Numeric. Systolic Blood Pressure at presentation (mmHg). <=90: +10 pts. 91-100: +8 pts. 101-120: +5 pts. 121-180: +1 pt. 181-200: +3 pts. >=201: +5 pts.

References

Subherwal S, Bach RG, Chen AY, et al. Baseline risk of major bleeding in non-ST-segment elevation myocardial infarction: the CRUSADE Bleeding Score. Circulation. 2009;119(14):1873-1882. doi:10.1161/CIRCULATIONAHA.108.828541

Examples

# Example 1: High Risk
# Hct 28 (+9), CrCl 25 (+35), HR 115 (+10), Female (+8), SBP 100 (+8), No other factors
# Score = 70
crusade_bleeding_score(28, 25, 115, "female", 0, 0, 0, 100)

# Example 2: Low Risk
# Hct 42 (0), CrCl 100 (+7), HR 70 (0), Male (0), SBP 130 (+1), No other factors
# Score = 8
crusade_bleeding_score(42, 100, 70, "male", 0, 0, 0, 130)