cliot (version 1.0.0)

das28_crp_rheumatoid_arthritis: Disease Activity Score-28 for Rheumatoid Arthritis (DAS28-CRP)

Description

Calculates the DAS28-CRP score, a standardized index of disease activity in Rheumatoid Arthritis. The score is calculated using the tender joint count (28 joints), swollen joint count (28 joints), C-Reactive Protein (CRP) level, and the patient's global assessment of health. It stratifies patients into Remission, Low, Moderate, or High disease activity.

Usage

das28_crp_rheumatoid_arthritis(tender_joint_count, swollen_joint_count, crp,
                               patient_global_health, crp_units = "mg/L")

Value

A list containing:

DAS28_CRP_Score

The calculated disease activity score.

Disease_Activity

Classification (Remission < 2.6, Low 2.6-3.2, Moderate 3.2-5.1, High > 5.1).

Arguments

tender_joint_count

Numeric (0-28). Number of tender joints identified during examination.

swollen_joint_count

Numeric (0-28). Number of swollen joints identified during examination.

crp

Numeric. C-Reactive Protein level.

patient_global_health

Numeric (0-100). Patient's global assessment of health on a visual analog scale (0 = best/no activity, 100 = worst/highest activity).

crp_units

String. Units for the CRP input. Options: "mg/L" (default) or "mg/dL".

References

Prevoo ML, van 't Hof MA, Kuper HH, et al. Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis. Arthritis Rheum. 1995;38(1):44-48. Wells G, Becker JC, Teng J, et al. Validation of the 28-joint Disease Activity Score (DAS28) and European League Against Rheumatism response criteria based on C-reactive protein against disease progression in patients with rheumatoid arthritis, and comparison with the DAS28 based on erythrocyte sedimentation rate. Ann Rheum Dis. 2009;68(6):954-960.

Examples

# Example 1: High Disease Activity
# 10 tender, 8 swollen, CRP 25 mg/L, Global Health 60
das28_crp_rheumatoid_arthritis(10, 8, 25, 60)

# Example 2: Remission
# 0 tender, 0 swollen, CRP 1.0 mg/L, Global Health 10
das28_crp_rheumatoid_arthritis(0, 0, 1.0, 10)