cliot (version 1.0.0)

dragon_score_stroke: DRAGON Score for Post-tPA Stroke Outcome

Description

Calculates the DRAGON score to predict the 3-month functional outcome (modified Rankin Scale) in acute ischemic stroke patients treated with intravenous tissue plasminogen activator (tPA). The score ranges from 0 to 10, with higher scores indicating a worse prognosis.

Usage

dragon_score_stroke(hyperdense_cerebral_artery, early_infarct_signs,
                    mrs_prestroke_gt_1, age, glucose, onset_to_treatment_gt_90,
                    baseline_nihss, glucose_units = "mg/dL")

Value

A list containing:

DRAGON_Score

The calculated total score (Range 0-10).

Risk_Category

Prognostic grouping (Good, Intermediate, Poor).

Outcome_Probability_3_Months

Estimated likelihood of good/poor outcome based on validation studies.

Arguments

hyperdense_cerebral_artery

Numeric (0 or 1). Presence of hyperdense cerebral artery sign on admission CT.

early_infarct_signs

Numeric (0 or 1). Presence of early infarct signs on admission CT.

mrs_prestroke_gt_1

Numeric (0 or 1). Pre-stroke modified Rankin Scale score > 1. (1 = Yes).

age

Numeric. Patient age in years. <65: 0 pts. 65-79: 1 pt. >=80: 2 pts.

glucose

Numeric. Baseline blood glucose level. (> 144 mg/dL or > 8 mmol/L adds 1 point).

onset_to_treatment_gt_90

Numeric (0 or 1). Onset to treatment time > 90 minutes. (1 = Yes).

baseline_nihss

Numeric. Baseline NIH Stroke Scale score. 0-4: 0 pts. 5-9: 1 pt. 10-15: 2 pts. >15: 3 pts.

glucose_units

String. Units for glucose input. Options: "mg/dL" (default) or "mmol/L".

Details

CT Findings Scoring: - Neither hyperdense artery nor early infarct signs: 0 points. - Either one present: 1 point. - Both present: 2 points.

References

Strbian D, Meretoja A, Ahlhelm FJ, et al. Predicting outcome of IV thrombolysis-treated ischemic stroke patients: the DRAGON score. Neurology. 2012;78(6):427-432. doi:10.1212/WNL.0b013e318245d2a9

Examples

# Example 1: Poor Prognosis
# Both CT signs (2), mRS>1 (1), Age 85 (2), Gluc 150 (1), Time >90 (1), NIHSS 20 (3)
# Score = 10
dragon_score_stroke(1, 1, 1, 85, 150, 1, 20)

# Example 2: Good Prognosis
# No CT signs, mRS 0, Age 60, Gluc 100, Time <90, NIHSS 4
# Score = 0
dragon_score_stroke(0, 0, 0, 60, 100, 0, 4)