cliot (version 1.0.0)

du_bois_ipf_score: du Bois Score for Idiopathic Pulmonary Fibrosis (IPF) Mortality

Description

Calculates the du Bois score to predict the 1-year risk of mortality in patients with Idiopathic Pulmonary Fibrosis (IPF). The score is based on age, history of respiratory hospitalization, baseline FVC, and the 24-week change in FVC.

Usage

du_bois_ipf_score(age, history_resp_hospitalization, baseline_fvc_percent,
                  fvc_change_24wk_percent)

Value

A list containing:

du_Bois_Score

The calculated risk score (Range 0-61).

Est_1_Year_Mortality

Estimated probability of death within 1 year.

Arguments

age

Numeric. Patient age in years. < 60: 0 pts. 60-69: 4 pts. >= 70: 8 pts.

history_resp_hospitalization

Numeric (0 or 1). History of respiratory hospitalization in the past 6 months. (1 = Yes, +14 pts).

baseline_fvc_percent

Numeric. Predicted baseline Forced Vital Capacity (FVC) percentage. >= 80: 0 pts. 66-79: 8 pts. 51-65: 13 pts. <= 50: 18 pts.

fvc_change_24wk_percent

Numeric. Change in predicted FVC over 24 weeks in percentage points. (e.g., -5 for a 5 >= -4.9: 0 pts (Stable/Improved). -5 to -9.9: 10 pts (Marginal Decline). <= -10: 21 pts (Significant Decline).

References

du Bois RM, et al. Ascertainment of individual risk of mortality for patients with idiopathic pulmonary fibrosis. Am J Respir Crit Care Med. 2011;184(4):459-466. doi:10.1164/rccm.201011-1790OC

Examples

# Example 1: High Risk
# 72yo (+8), Prior Hosp (+14), FVC 55% (+13), Decline -12% (+21)
# Score = 56
du_bois_ipf_score(72, 1, 55, -12)

# Example 2: Low Risk
# 55yo (0), No Hosp (0), FVC 85% (0), Stable FVC (0)
# Score = 0
du_bois_ipf_score(55, 0, 85, 0)