cliot (version 1.0.0)

fibrotic_nash_index: Fibrotic NASH Index (FNI)

Description

Calculates the Fibrotic NASH Index (FNI) to predict the presence of advanced fibrosis in patients with Nonalcoholic Steatohepatitis (NASH). This simple index uses three common laboratory values: AST, HDL cholesterol, and HbA1c.

Usage

fibrotic_nash_index(ast, hdl_cholesterol, hba1c)

Value

A list containing:

FNI_Score

The calculated risk score (probability between 0 and 1).

Risk_Category

Classification (Low < 0.10, Intermediate 0.10-0.33, High > 0.33).

Interpretation

Clinical meaning of the risk category.

Arguments

ast

Numeric. Aspartate Aminotransferase level (U/L).

hdl_cholesterol

Numeric. High-Density Lipoprotein Cholesterol level (mg/dL).

hba1c

Numeric. Hemoglobin A1c percentage.

References

Loomba R, et al. Fibrotic NASH Index: A Simple Model to Predict Advanced Fibrosis in Patients With Nonalcoholic Steatohepatitis. Hepatology. 2019.

Examples

# Example 1: High Risk
# AST 80, HDL 30, HbA1c 8.5
fibrotic_nash_index(80, 30, 8.5)

# Example 2: Low Risk
# AST 20, HDL 60, HbA1c 5.0
fibrotic_nash_index(20, 60, 5.0)