fong_crs_score: Fong Clinical Risk Score (CRS) for Colorectal Cancer Recurrence

Description

Calculates the Fong Clinical Risk Score (CRS) to predict recurrence and survival in patients undergoing resection of hepatic metastases from colorectal cancer. The score is based on five clinical criteria: nodal status of the primary tumor, disease-free interval, number of hepatic tumors, preoperative CEA level, and size of the largest hepatic tumor.

Usage

fong_crs_score(nodal_status_primary, disease_free_interval_lt_12mo,
               num_tumors_gt_1, preop_cea_gt_200, largest_tumor_gt_5cm)

Value

A list containing:

Fong_Score: The calculated risk score (Range 0-5).
Risk_Group: Classification (Low, Intermediate, High).
Est_5_Year_Survival: Estimated 5-year survival probability.
Median_Survival: Estimated median survival time in months.

Arguments

nodal_status_primary: Numeric (0 or 1). Node-positive primary tumor. (1 = Yes, +1 point).
disease_free_interval_lt_12mo: Numeric (0 or 1). Disease-free interval from primary diagnosis to discovery of liver metastases < 12 months. (1 = Yes, +1 point).
num_tumors_gt_1: Numeric (0 or 1). Number of hepatic tumors > 1. (1 = Yes, +1 point).
preop_cea_gt_200: Numeric (0 or 1). Preoperative Carcinoembryonic Antigen (CEA) level > 200 ng/mL. (1 = Yes, +1 point).
largest_tumor_gt_5cm: Numeric (0 or 1). Size of the largest hepatic tumor > 5 cm. (1 = Yes, +1 point).

References

Fong Y, Fortner J, Sun RL, Brennan MF, Blumgart LH. Clinical score for predicting recurrence after hepatic resection for metastatic colorectal cancer: analysis of 1001 consecutive cases. Ann Surg. 1999;230(3):309-318. doi:10.1097/00000658-199909000-00004

Examples

Run this code


# Example 1: High Risk
# Node+ Primary, DFI < 12mo, Multiple tumors, CEA 50, Size 3cm
# Score = 1 + 1 + 1 + 0 + 0 = 3
fong_crs_score(1, 1, 1, 0, 0)

# Example 2: Low Risk
# Node Negative, DFI > 12mo, Single tumor, CEA < 200, Size < 5cm
# Score = 0
fong_crs_score(0, 0, 0, 0, 0)

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