cliot (version 1.0.0)

garfield_af_risk_score: GARFIELD-AF Risk Calculator

Description

Structures the clinical inputs for the GARFIELD-AF Risk Calculator. This integrated risk tool estimates the 1-year and 2-year risks of all-cause mortality, stroke/systemic embolism, and major bleeding in patients with newly diagnosed atrial fibrillation. It accounts for demographics, vital signs, comorbidities, and antithrombotic treatment.

Usage

garfield_af_risk_score(sex, age, weight_kg, heart_rate, systolic_bp,
                       chf_history, acs_history, history_stroke_tia,
                       history_bleeding, ckd_stage_3_to_5, diabetes,
                       treatment_type)

Value

A list containing:

Patient_Profile

Summary of demographics and vitals.

Risk_Factors_Identified

List of positive risk factors contributing to the score.

Note

Guidance regarding the regression model used for the final percentage output.

Arguments

sex

String. Patient sex ("Male" or "Female").

age

Numeric. Patient age in years.

weight_kg

Numeric. Patient weight in kilograms.

heart_rate

Numeric. Heart rate in beats per minute.

systolic_bp

Numeric. Systolic blood pressure in mmHg.

chf_history

Numeric (0 or 1). History of Congestive Heart Failure. (1 = Yes).

acs_history

Numeric (0 or 1). History of Acute Coronary Syndrome. (1 = Yes).

history_stroke_tia

Numeric (0 or 1). History of Stroke, TIA, or Systemic Embolism. (1 = Yes).

history_bleeding

Numeric (0 or 1). History of bleeding. (1 = Yes).

ckd_stage_3_to_5

Numeric (0 or 1). Moderate to severe Chronic Kidney Disease (Stage 3-5). (1 = Yes).

diabetes

Numeric (0 or 1). Diabetes Mellitus. (1 = Yes).

treatment_type

String. Current antithrombotic treatment. Options: "none", "vka" (Vitamin K Antagonist), "doac" (Direct Oral Anticoagulant), "antiplatelet", "combination".

References

Fox KAA, Lucas JE, Pieper KS, et al. Improved risk stratification of patients with atrial fibrillation: an integrated GARFIELD-AF tool for the prediction of mortality, stroke and bleeding in patients with and without anticoagulation. BMJ Open. 2017;7(12):e017157. doi:10.1136/bmjopen-2017-017157

Examples

# Example 1: Multiple Comorbidities
# 75yo Male, CHF, Prior Stroke, on VKA
garfield_af_risk_score("male", 75, 80, 72, 130, 1, 0, 1, 0, 0, 0, "vka")

# Example 2: Low Comorbidity
# 55yo Female, No history, on Antiplatelet
garfield_af_risk_score("female", 55, 60, 68, 120, 0, 0, 0, 0, 0, 0, "antiplatelet")