cliot (version 1.0.0)

hydroxychloroquine_dosing: Hydroxychloroquine (Plaquenil) Dosing Calculator

Description

Calculates recommended hydroxychloroquine dosing based on patient weight and indication. Incorporates the American Academy of Ophthalmology (AAO) guidelines recommending a maximum daily dose of < 5 mg/kg actual body weight to minimize the risk of retinal toxicity for chronic use (Lupus/RA).

Usage

hydroxychloroquine_dosing(weight_kg, indication)

Value

A list containing:

Recommended_Dosing

The calculated dose based on weight and indication guidelines.

Safety_Guidance

Warnings regarding maximum safe dosage, particularly for retinal safety.

Arguments

weight_kg

Numeric. Patient actual body weight in kilograms.

indication

String. Indication for treatment. Options: "lupus", "rheumatoid_arthritis", "malaria_prophylaxis", "malaria_treatment".

References

Marmor MF, Kellner U, Lai TY, et al. Recommendations on Screening for Chloroquine and Hydroxychloroquine Retinopathy (2016 Revision). Ophthalmology. 2016;123(6):1386-1394. doi:10.1016/j.ophtha.2016.01.058

Examples

# Example 1: Lupus Dosing (Chronic)
# 60kg patient (Max 5mg/kg = 300mg)
hydroxychloroquine_dosing(60, "lupus")

# Example 2: Malaria Treatment (Acute)
# 50kg patient
hydroxychloroquine_dosing(50, "malaria_treatment")