cliot (version 1.0.0)

improvedd_vte_score: IMPROVEDD VTE Risk Score

Description

Calculates the IMPROVEDD (IMPROVE + D-Dimer) VTE Risk Score. This tool enhances the original IMPROVE score by adding elevated D-dimer as a weighted risk factor, improving the identification of hospitalized medical patients at high risk for venous thromboembolism (VTE).

Usage

improvedd_vte_score(previous_vte, known_thrombophilia, lower_limb_paralysis,
                    current_cancer, immobilized_ge_7days, icu_ccu_stay,
                    age_gt_60, d_dimer_ge_2x_uln)

Value

A list containing:

IMPROVEDD_Score

The calculated score (Range 0-14).

Risk_Category

Classification (Low 0-1, Moderate 2-3, High >=4).

VTE_Risk_42_Day

Estimated 42-day VTE risk percentage.

Arguments

previous_vte

Numeric (0 or 1). History of previous VTE. (1 = Yes, +3 points).

known_thrombophilia

Numeric (0 or 1). Known thrombophilia. (1 = Yes, +2 points).

lower_limb_paralysis

Numeric (0 or 1). Current lower-limb paralysis or paresis. (1 = Yes, +2 points).

current_cancer

Numeric (0 or 1). Active cancer. (1 = Yes, +2 points).

immobilized_ge_7days

Numeric (0 or 1). Immobilization >= 7 days. (1 = Yes, +1 point).

icu_ccu_stay

Numeric (0 or 1). Stay in ICU or CCU. (1 = Yes, +1 point).

age_gt_60

Numeric (0 or 1). Age > 60 years. (1 = Yes, +1 point).

d_dimer_ge_2x_uln

Numeric (0 or 1). D-dimer level >= 2 times the Upper Limit of Normal (ULN). (1 = Yes, +2 points).

References

Gibson CM, Spyropoulos AC, Cohen AT, et al. The IMPROVEDD VTE Risk Score: A New Model for Predicting Venous Thromboembolism in Acutely Ill Hospitalized Medical Patients. TH Open. 2017;1(1):e56-e65. doi:10.1055/s-0037-1604432

Examples

# Example 1: High Risk
# Prior VTE (+3), D-Dimer High (+2)
# Score = 5
improvedd_vte_score(1, 0, 0, 0, 0, 0, 0, 1)

# Example 2: Moderate Risk
# Age >60 (+1), Immobilized (+1)
# Score = 2
improvedd_vte_score(0, 0, 0, 0, 1, 0, 1, 0)