lent_prognostic_score: LENT Prognostic Score for Malignant Pleural Effusion

Description

Calculates the LENT score (Pleural fluid LDH, ECOG performance status, Neutrophil-to-lymphocyte ratio, Tumor type) to predict survival in patients with malignant pleural effusion. It stratifies patients into Low, Moderate, and High risk groups.

Usage

lent_prognostic_score(pleural_ldh, ecog_score, serum_nlr, tumor_type)

Value

A list containing:

LENT_Score: The calculated total score (Range 0-7).
Risk_Category: Classification (Low 0-1, Moderate 2-4, High 5-7).
Median_Survival: Estimated median survival time in days/months.

Arguments

pleural_ldh: Numeric. Lactate dehydrogenase level in pleural fluid (IU/L). (> 1500 IU/L adds 1 point).
ecog_score: Numeric (0-4). Eastern Cooperative Oncology Group performance status. 0: 0 pts. 1: 1 pt. 2: 2 pts. 3-4: 3 pts.
serum_nlr: Numeric. Serum neutrophil-to-lymphocyte ratio. (> 9 adds 1 point).
tumor_type: String. Primary tumor type. "mesothelioma", "hematologic": 0 pts (Low risk). "breast", "gynecologic", "renal", "sarcoma": 1 pt (Moderate risk). "lung", "other": 2 pts (High risk).

References

Clive AO, Kahan BC, Hooper CE, et al. Predicting survival in malignant pleural effusion: development and validation of the LENT prognostic score. Thorax. 2014;69(12):1098-1104. doi:10.1136/thoraxjnl-2014-205285

Examples

Run this code


# Example 1: Low Risk
# LDH 1000, ECOG 0, NLR 5, Breast Cancer
# Score = 0 + 0 + 0 + 1 = 1
lent_prognostic_score(1000, 0, 5, "breast")

# Example 2: High Risk
# LDH 2000 (+1), ECOG 3 (+3), NLR 12 (+1), Lung Cancer (+2)
# Score = 7
lent_prognostic_score(2000, 3, 12, "lung")

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