cliot (version 1.0.0)

lights_criteria_effusion: Light's Criteria for Pleural Effusion

Description

Applies Light's Criteria to differentiate between transudative and exudative pleural effusions. An effusion is classified as exudative if at least one of the three criteria is met: 1. Pleural fluid protein / Serum protein > 0.5 2. Pleural fluid LDH / Serum LDH > 0.6 3. Pleural fluid LDH > 2/3 * Serum LDH Upper Limit of Normal (ULN)

Usage

lights_criteria_effusion(pleural_protein, serum_protein, pleural_ldh,
                         serum_ldh, serum_ldh_uln)

Value

A list containing:

Classification

"Exudative" or "Transudative".

Criteria_Met

A list of the specific criteria that triggered the exudative classification.

Calculated_Values

The calculated ratios and thresholds used.

Arguments

pleural_protein

Numeric. Pleural fluid protein level (g/dL).

serum_protein

Numeric. Serum protein level (g/dL).

pleural_ldh

Numeric. Pleural fluid Lactate Dehydrogenase (LDH) level (U/L).

serum_ldh

Numeric. Serum Lactate Dehydrogenase (LDH) level (U/L).

serum_ldh_uln

Numeric. The laboratory's upper limit of normal for serum LDH (U/L).

References

Light RW, Macgregor MI, Luchsinger PC, Ball WC Jr. Pleural effusions: the diagnostic separation of transudates and exudates. Ann Intern Med. 1972;77(4):507-513. doi:10.7326/0003-4819-77-4-507

Examples

# Example 1: Exudative (High Protein Ratio)
# P-Prot 4.0, S-Prot 6.0 (Ratio 0.66), LDH normal
lights_criteria_effusion(4.0, 6.0, 100, 200, 250)

# Example 2: Transudative
# P-Prot 2.0, S-Prot 7.0 (Ratio 0.28), P-LDH 80, S-LDH 200, ULN 250
# All ratios low
lights_criteria_effusion(2.0, 7.0, 80, 200, 250)