cliot (version 1.0.0)

mayo_uc_score: Mayo Score / Disease Activity Index (DAI) for Ulcerative Colitis

Description

Calculates the Mayo Score (also known as the Disease Activity Index) for Ulcerative Colitis. This tool assesses disease severity based on four criteria: stool frequency, rectal bleeding, endoscopic findings, and the physician's global assessment.

Usage

mayo_uc_score(stool_frequency, rectal_bleeding, endoscopic_findings,
              physician_global_assessment)

Value

A list containing:

Mayo_Score

The calculated total score (Range 0-12).

Disease_Activity

Interpretation of disease severity (Remission, Mild, Moderate, Severe).

Arguments

stool_frequency

Numeric (0-3). Stool frequency relative to normal. 0: Normal number of stools. 1: 1-2 stools more than normal. 2: 3-4 stools more than normal. 3: 5 or more stools more than normal.

rectal_bleeding

Numeric (0-3). Rectal bleeding. 0: No blood seen. 1: Streaks of blood with stool less than half the time. 2: Obvious blood with stool most of the time. 3: Blood alone passes.

endoscopic_findings

Numeric (0-3). Findings on endoscopy (flexible proctosigmoidoscopy). 0: Normal or inactive disease. 1: Mild disease (erythema, decreased vascular pattern, mild friability). 2: Moderate disease (marked erythema, lack of vascular pattern, friability, erosions). 3: Severe disease (spontaneous bleeding, ulceration).

physician_global_assessment

Numeric (0-3). Physician's Global Assessment. 0: Normal. 1: Mild disease. 2: Moderate disease. 3: Severe disease.

References

Schroeder KW, Tremaine WJ, Ilstrup DM. Coated oral 5-aminosalicylic acid therapy for mildly to moderately active ulcerative colitis. N Engl J Med. 1987;317(26):1625-1629. doi:10.1056/NEJM198712243172603

Examples

# Example 1: Moderate Activity
# Freq +1 (1), Bleeding +1 (1), Endo Moderate (2), PGA Moderate (2)
# Score = 6
mayo_uc_score(1, 1, 2, 2)

# Example 2: Severe Activity
# Freq +3 (3), Blood alone (3), Endo Severe (3), PGA Severe (3)
# Score = 12
mayo_uc_score(3, 3, 3, 3)