cliot (version 1.0.0)

mdrd_gfr_equation: MDRD GFR Equation (IDMS-Traceable)

Description

Calculates the estimated Glomerular Filtration Rate (eGFR) using the Modification of Diet in Renal Disease (MDRD) Study equation. This version uses the IDMS-traceable formula (standardized serum creatinine). Note: The MDRD equation has largely been superseded by CKD-EPI for general use but remains relevant in certain clinical contexts or historical data comparisons.

Usage

mdrd_gfr_equation(creatinine, age, sex, race, creatinine_units = "mg/dL")

Value

A list containing:

MDRD_GFR

The estimated GFR in mL/min/1.73m^2.

CKD_Stage

Staging classification based on the calculated GFR.

Arguments

creatinine

Numeric. Serum Creatinine level.

age

Numeric. Patient age in years.

sex

String. Patient sex ("Male" or "Female").

race

String. Patient race ("black" or "other"). The equation applies a correction factor (x1.212) for African American patients.

creatinine_units

String. Units for creatinine input. Options: "mg/dL" (default) or "umol/L" (or "micromol/L").

References

Levey AS, Coresh J, Greene T, et al. Using standardized serum creatinine values in the modification of diet in renal disease study equation for estimating glomerular filtration rate. Ann Intern Med. 2006;145(4):247-254. doi:10.7326/0003-4819-145-4-200608150-00004

Examples

# Example 1: Healthy Adult
# Cr 0.9, 40yo Male, Non-Black
# GFR = 175 * (0.9)^-1.154 * (40)^-0.203 = ~98
mdrd_gfr_equation(0.9, 40, "male", "other")

# Example 2: Chronic Kidney Disease
# Cr 2.5, 65yo Female, Black
# GFR = 175 * (2.5)^-1.154 * (65)^-0.203 * 0.742 * 1.212 = ~23
mdrd_gfr_equation(2.5, 65, "female", "black")