cliot (version 1.0.0)

mskcc_gist_recurrence_risk: MSKCC Risk of Recurrence for GIST

Description

Calculates the likelihood of recurrence-free survival (RFS) at 2 and 5 years after complete surgical resection of a localized primary Gastrointestinal Stromal Tumor (GIST). This nomogram (Goldjsher et al.) uses tumor size, location, and mitotic index.

Usage

mskcc_gist_recurrence_risk(tumor_size_cm, tumor_site, mitotic_index_ge_5)

Value

A list containing:

Recurrence_Free_Survival_2yr

Estimated percentage of patients recurrence-free at 2 years.

Recurrence_Free_Survival_5yr

Estimated percentage of patients recurrence-free at 5 years.

Risk_of_Recurrence_2yr

Estimated percentage risk of recurrence within 2 years.

Risk_of_Recurrence_5yr

Estimated percentage risk of recurrence within 5 years.

Arguments

tumor_size_cm

Numeric. Largest diameter of the tumor in centimeters.

tumor_site

String. Location of the tumor. Options: "stomach", "small_intestine", "colon_rectum", "other".

mitotic_index_ge_5

Numeric (0 or 1). Mitotic index >= 5 per 50 High Power Fields (HPF). (1 = Yes).

References

Goldjsher D, Joanis V, DeMatteo RP, et al. Development and validation of a prognostic nomogram for recurrence-free survival after complete surgical resection of localized, primary gastrointestinal stromal tumor: a retrospective analysis. Lancet Oncol. 2009;10(11):1045-1052. doi:10.1016/S1470-2045(09)70242-6

Examples

# Example 1: Low Risk
# 3cm Stomach GIST, Low Mitosis
mskcc_gist_recurrence_risk(3, "stomach", 0)

# Example 2: High Risk
# 12cm Small Bowel GIST, High Mitosis
mskcc_gist_recurrence_risk(12, "small_intestine", 1)