cliot (version 1.0.0)

myxedema_coma_score: Myxedema Coma Diagnostic Score

Description

Calculates the diagnostic score for myxedema coma. This tool aggregates clinical and laboratory findings (thermoregulation, CNS status, GI symptoms, cardiovascular dysfunction, metabolic disturbances, and precipitating events) to assess the likelihood of myxedema coma in patients with severe hypothyroidism.

Usage

myxedema_coma_score(temp_c, cns_status, gi_symptoms, precipitating_event,
                    bradycardia, ecg_changes, hypotension, hyponatremia,
                    hypoglycemia, hypoxemia_hypercapnia)

Value

A list containing:

Diagnostic_Score

The calculated total score.

Interpretation

Diagnostic likelihood (Unlikely <25, Suggestive 25-59, Diagnostic >=60).

Arguments

temp_c

Numeric. Body temperature in degrees Celsius. (>35: 0 pts, 32-35: 10 pts, <32: 20 pts).

cns_status

String. Central Nervous System status. Options: "absent" (0 pts), "drowsy_lethargic" (10 pts), "obtunded" (15 pts), "stupor_coma" (20 pts).

gi_symptoms

String. Gastrointestinal symptoms. Options: "absent" (0 pts), "anorexia_pain_constipation" (5 pts), "decreased_motility_ileus" (10 pts).

precipitating_event

Numeric (0 or 1). Presence of a precipitating event (e.g., infection, surgery, drug exposure). (1 = Yes, +10 pts).

bradycardia

Numeric (0 or 1). Bradycardia present. (1 = Yes, +10 pts).

ecg_changes

Numeric (0 or 1). ECG changes present (e.g., low voltage, prolonged QT, heart block). (1 = Yes, +10 pts).

hypotension

Numeric (0 or 1). Hypotension or cardiogenic shock present. (1 = Yes, +10 pts).

hyponatremia

Numeric (0 or 1). Hyponatremia present. (1 = Yes, +10 pts).

hypoglycemia

Numeric (0 or 1). Hypoglycemia present. (1 = Yes, +10 pts).

hypoxemia_hypercapnia

Numeric (0 or 1). Hypoxemia or hypercapnia present. (1 = Yes, +10 pts).

References

Popoveniuc G, Chandra T, Sud A, et al. A diagnostic scoring system for myxedema coma. Endocr Pract. 2014;20(8):808-817. doi:10.4158/EP13303.OR

Examples

# Example 1: Diagnostic (Score 70)
# Temp 30C (20), Coma (20), Ileus (10), Precipitant (10), Bradycardia (10)
myxedema_coma_score(30, "stupor_coma", "decreased_motility_ileus", 1, 1, 0, 0, 0, 0, 0)

# Example 2: Suggestive (Score 30)
# Temp 34C (10), Lethargic (10), Hypoglycemia (10)
myxedema_coma_score(34, "drowsy_lethargic", "absent", 0, 0, 0, 0, 0, 1, 0)