cliot (version 1.0.0)

neutrophil_lymphocyte_ratio: Neutrophil-Lymphocyte Ratio (NLR)

Description

Calculates the Neutrophil-Lymphocyte Ratio (NLR), a readily available biomarker of systemic inflammation and stress. It is used as a prognostic indicator in various conditions including sepsis, COVID-19, cardiovascular disease, and solid tumors. Elevated NLR is generally associated with worse outcomes.

Usage

neutrophil_lymphocyte_ratio(neutrophil_count, lymphocyte_count)

Value

A list containing:

NLR

The calculated ratio (Neutrophils / Lymphocytes).

Interpretation

General clinical context regarding normal vs. elevated ranges.

Arguments

neutrophil_count

Numeric. The absolute neutrophil count (ANC) or percentage of neutrophils.

lymphocyte_count

Numeric. The absolute lymphocyte count (ALC) or percentage of lymphocytes. Note: Inputs must use the same unit (absolute count or percentage) for the ratio to be valid.

References

Zahorec R. Ratio of neutrophil to lymphocyte counts--rapid and simple parameter of systemic inflammation and stress in critically ill. Bratisl Lek Listy. 2001;102(1):5-14. Liu Y, Du X, Chen J, et al. Neutrophil-to-lymphocyte ratio as an independent risk factor for mortality in hospitalized patients with COVID-19. J Infect. 2020;81(1):e6-e12. doi:10.1016/j.jinf.2020.04.002

Examples

# Example 1: Normal Range
# Neutrophils 4000, Lymphocytes 2000
# NLR = 2.0
neutrophil_lymphocyte_ratio(4000, 2000)

# Example 2: Elevated (Severe Infection/Stress)
# Neutrophils 8000, Lymphocytes 500
# NLR = 16.0
neutrophil_lymphocyte_ratio(8000, 500)