Calculates the predicted 6-hour cumulative sodium output based on a single spot urine sodium sample taken 2 hours after loop diuretic administration. This tool helps evaluate diuretic resistance and guide titration in patients with acute heart failure.
Usage
nrpe_diuretic_response(spot_urine_sodium)
Value
A list containing:
Predicted_6hr_Sodium_Output_mmol
The estimated total sodium excretion over 6 hours.
Interpretation
Assessment of response adequacy based on the common threshold of 50 mmol/L.
Arguments
spot_urine_sodium
Numeric. Spot urine sodium concentration (mmol/L or mEq/L) measured 2 hours after diuretic administration.
References
Rao VS, Ivey-Miranda JB, Cox ZL, et al. Natriuretic Equation to Predict Loop Diuretic Response in Patients With Heart Failure. J Am Coll Cardiol. 2019;74(7):861-868. doi:10.1016/j.jacc.2019.06.028