cliot (version 1.0.0)

ohts_risk_score: Ocular Hypertension Treatment Study (OHTS) Calculator

Description

Calculates the 5-year risk of developing Primary Open-Angle Glaucoma (POAG) in patients with Ocular Hypertension. This function utilizes the point-based scoring system derived from the OHTS and European Glaucoma Prevention Study (EGPS) pooled data. It considers Age, Intraocular Pressure (IOP), Central Corneal Thickness (CCT), Vertical Cup-Disc Ratio (VCDR), and Pattern Standard Deviation (PSD).

Usage

ohts_risk_score(age, iop, cct, vcdr, psd)

Value

A list containing:

OHTS_Points

The calculated total risk points (Range 0-13+).

Five_Year_POAG_Risk

The estimated percentage risk of developing POAG within 5 years.

Risk_Category

Classification of risk (Low, Intermediate, High).

Arguments

age

Numeric. Patient age in years.

iop

Numeric. Intraocular Pressure in mm Hg (mean of measurements).

cct

Numeric. Central Corneal Thickness in micrometers.

vcdr

Numeric. Vertical Cup-to-Disc Ratio (0.0 to 1.0).

psd

Numeric. Pattern Standard Deviation (dB) from visual field testing (Humphrey 24-2 or 30-2).

References

Gordon MO, Beiser JA, Brandt JD, et al. The Ocular Hypertension Treatment Study: baseline factors that predict the onset of primary open-angle glaucoma. Arch Ophthalmol. 2002;120(6):714-720. doi:10.1001/archopht.120.6.714 OHTS/EGPS Investigators. A Validated Prediction Model for the Development of Primary Open-Angle Glaucoma in Individuals with Ocular Hypertension. Ophthalmology. 2007;114(1):10-19.

Examples

# Example 1: Low Risk
# Age 45, IOP 21, CCT 600, VCDR 0.3, PSD 1.5
# Points: 0+0+0+0+0 = 0
ohts_risk_score(45, 21, 600, 0.3, 1.5)

# Example 2: High Risk
# Age 72, IOP 28, CCT 540, VCDR 0.7, PSD 2.8
# Points: 3+3+2+2+2 = 12
ohts_risk_score(72, 28, 540, 0.7, 2.8)