cliot (version 1.0.0)

orbit_bleeding_risk_score: ORBIT Bleeding Risk Score for Atrial Fibrillation

Description

Calculates the ORBIT Bleeding Risk Score to predict major bleeding in patients with atrial fibrillation on oral anticoagulation. The score uses five clinical variables: Older age, Reduced hemoglobin/hematocrit/anemia, Bleeding history, Insufficient kidney function, and Treatment with antiplatelet agents.

Usage

orbit_bleeding_risk_score(age_gt_74, reduced_hemoglobin_or_hct_anemia,
                          bleeding_history, insufficient_kidney_function,
                          treatment_with_antiplatelet)

Value

A list containing:

ORBIT_Score

The calculated risk score (Range 0-7).

Risk_Group

Classification (Low: 0-2, Medium: 3, High: 4-7).

Bleeding_Risk

Estimated major bleeding rate per 100 patient-years.

Arguments

age_gt_74

Numeric (0 or 1). Older Age (>74 years). (1 = Yes, +1 point).

reduced_hemoglobin_or_hct_anemia

Numeric (0 or 1). Reduced hemoglobin (<13 mg/dL for men, <12 mg/dL for women) or hematocrit (<40% for men, <36% for women) or history of anemia. (1 = Yes, +2 points).

bleeding_history

Numeric (0 or 1). Bleeding History (GI bleed, intracranial hemorrhage, or hemorrhagic stroke). (1 = Yes, +2 points).

insufficient_kidney_function

Numeric (0 or 1). Insufficient kidney function (eGFR <60 mg/dL/1.73 m^2). (1 = Yes, +1 point).

treatment_with_antiplatelet

Numeric (0 or 1). Treatment with antiplatelet agents. (1 = Yes, +1 point).

References

O'Brien EC, Simon DN, Thomas LE, et al. The ORBIT bleeding score: a simple bedside score to assess bleeding risk in atrial fibrillation. Eur Heart J. 2015;36(46):3258-3264. doi:10.1093/eurheartj/ehv476

Examples

# Example 1: High Risk
# Anemia (+2), Bleeding Hx (+2), Antiplatelet (+1)
# Score = 5
orbit_bleeding_risk_score(0, 1, 1, 0, 1)

# Example 2: Low Risk
# Age 70 (0), No other risk factors
# Score = 0
orbit_bleeding_risk_score(0, 0, 0, 0, 0)