promise_score_mpe: PROMISE Score for Malignant Pleural Effusion

Description

Calculates the PROMISE (PROgnostic score for Malignant Pleural Effusion) score to predict 3-month mortality and estimate median survival in patients with malignant pleural effusion (MPE). The score combines clinical and laboratory variables including hemoglobin, CRP, WBC, ECOG performance status, and cancer type.

Usage

promise_score_mpe(hemoglobin_g_dl, crp_mg_l, wbc_count, ecog_score, cancer_type)

Value

A list containing:

PROMISE_Score: The calculated total score (Range 0-13).
Risk_Group: Classification (Group A-D).
Est_3_Month_Survival: Estimated 3-month survival probability.
Median_Survival: Estimated median survival time in days.

Arguments

hemoglobin_g_dl: Numeric. Serum hemoglobin level in g/dL. >= 12: 0 pts. 10 - <12: 1 pt. < 10: 2 pts.
crp_mg_l: Numeric. Serum C-Reactive Protein level in mg/L. < 50: 0 pts. 50 - <100: 1 pt. >= 100: 2 pts.
wbc_count: Numeric. White Blood Cell count in x10^9/L. < 12: 0 pts. >= 12: 1 pt.
ecog_score: Numeric. ECOG Performance Status (0-4). 0-1: 0 pts. 2: 2 pts. 3-4: 4 pts.
cancer_type: String. Type of primary cancer. "hematologic", "breast", "gynecologic": 0 pts. "mesothelioma": 4 pts. "lung", "gi", "gu", "sarcoma", "melanoma", "other": 2 pts.

References

Psallidas I, Kanellakis NI, Gerry S, et al. Development and validation of the PROMISE score to predict survival in patients with malignant pleural effusion. Lancet Oncol. 2018;19(7):930-939. doi:10.1016/S1470-2045(18)30294-7

Examples

Run this code


# Example 1: Low Risk (Group A)
# Hb 13 (0), CRP 10 (0), WBC 6 (0), ECOG 0 (0), Breast CA (0)
# Score = 0
promise_score_mpe(13, 10, 6, 0, "breast")

# Example 2: High Risk (Group C)
# Hb 11 (1), CRP 80 (1), WBC 9 (0), ECOG 2 (2), Lung CA (2)
# Score = 6
promise_score_mpe(11, 80, 9, 2, "lung")

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