cliot (version 1.0.0)

ransons_criteria: Ranson's Criteria for Pancreatitis Mortality

Description

Calculates the Ranson's Criteria score to predict the mortality risk of patients with acute pancreatitis. The score evaluates 11 parameters measured at admission and at 48 hours. Different scoring thresholds apply depending on whether the pancreatitis is biliary (gallstone-induced) or non-biliary (e.g., alcoholic).

Usage

ransons_criteria(age, wbc_count, glucose_mg_dl, ldh, ast,
                 hct_fall_percent, bun_increase_mg_dl, calcium_mg_dl,
                 pao2_mmhg, base_deficit_meq_l, fluid_sequestration_liters,
                 etiology = "non_biliary")

Value

A list containing:

Ranson_Score

The calculated total score (Range 0-11 for non-biliary, 0-10 for biliary).

Mortality_Risk

Estimated mortality percentage associated with the score.

Arguments

age

Numeric. Patient age in years.

wbc_count

Numeric. White Blood Cell count (cells/mm^3 or uL).

glucose_mg_dl

Numeric. Blood glucose level in mg/dL.

ldh

Numeric. Lactate Dehydrogenase level in IU/L.

ast

Numeric. Aspartate Aminotransferase level in IU/L.

hct_fall_percent

Numeric. Drop in hematocrit percentage points within 48 hours.

bun_increase_mg_dl

Numeric. Increase in Blood Urea Nitrogen in mg/dL within 48 hours.

calcium_mg_dl

Numeric. Serum Calcium level in mg/dL at 48 hours.

pao2_mmhg

Numeric. Arterial PO2 in mmHg at 48 hours. (Only scored for non-biliary etiology in standard Ranson's, though often collected).

base_deficit_meq_l

Numeric. Base deficit in mEq/L at 48 hours.

fluid_sequestration_liters

Numeric. Estimated fluid sequestration in Liters at 48 hours.

etiology

String. Cause of pancreatitis. Options: "non_biliary" (default) or "biliary".

References

Ranson JH, Rifkind KM, Roses DF, et al. Prognostic signs and the role of operative management in acute pancreatitis. Surg Gynecol Obstet. 1974;139(1):69-81. Ranson JH. Etiological and prognostic factors in human acute pancreatitis: a review. Am J Gastroenterol. 1982;77(9):633-638.

Examples

# Example 1: Non-Biliary (Alcohol), Severe
# Age 60 (+1), WBC 18k (+1), Glu 250 (+1), LDH 400 (+1), AST 300 (+1)
# 48h: Hct drop 12 (+1), BUN up 10 (+1), Ca 7 (+1), PaO2 55 (+1), BD 5 (+1), Fluid 7 (+1)
# Score = 11
ransons_criteria(60, 18000, 250, 400, 300, 12, 10, 7, 55, 5, 7, "non_biliary")

# Example 2: Biliary, Moderate
# Age 75 (+1), WBC 19k (+1), Glu 150 (0), LDH 350 (0), AST 200 (0)
# 48h: Hct drop 5 (0), BUN up 1 (0), Ca 9 (0), PaO2 70, BD 2 (0), Fluid 3 (0)
# Score = 2
ransons_criteria(75, 19000, 150, 350, 200, 5, 1, 9, 70, 2, 3, "biliary")