cliot (version 1.0.0)

rasp_hiv_risk: HIV Needle Stick Risk Assessment Stratification Protocol (RASP)

Description

Estimates the risk of HIV transmission following occupational exposure (needle stick, mucous membrane, or non-intact skin contact) and provides Post-Exposure Prophylaxis (PEP) recommendations based on CDC guidelines.

Usage

rasp_hiv_risk(source_status, exposure_type, deep_injury_or_visible_blood,
              source_viral_load_high)

Value

A list containing:

Estimated_Transmission_Risk

The estimated probability of seroconversion (e.g., 0.3% for percutaneous).

PEP_Recommendation

Guidance on initiating Post-Exposure Prophylaxis.

Arguments

source_status

String. Status of the source patient. Options: "positive", "negative", "unknown".

exposure_type

String. Type of exposure. Options: "percutaneous" (needle stick/cut), "mucous_membrane" (splash to eye/mouth), "non_intact_skin" (abrasion/dermatitis).

deep_injury_or_visible_blood

Numeric (0 or 1). Was the injury deep or was there visible blood on the device? (1 = Yes).

source_viral_load_high

Numeric (0 or 1). Is the source known to have a high viral load or acute HIV infection? (1 = Yes).

References

Kuhar DT, Henderson DK, Struble KA, et al. Updated US Public Health Service Guidelines for the Management of Occupational Exposures to Human Immunodeficiency Virus and Recommendations for Postexposure Prophylaxis. Infect Control Hosp Epidemiol. 2013;34(9):875-892. doi:10.1086/672271

Examples

# Example 1: High Risk Needlestick
# Source Positive, Percutaneous, Deep injury
rasp_hiv_risk("positive", "percutaneous", 1, 1)

# Example 2: Lower Risk Splash
# Source Positive, Mucous membrane splash
rasp_hiv_risk("positive", "mucous_membrane", 0, 0)

# Example 3: Source Negative
# No risk
rasp_hiv_risk("negative", "percutaneous", 1, 0)