cliot (version 1.0.0)

rebound_hyperbilirubinemia_score: Rebound Hyperbilirubinemia Risk Score

Description

Calculates the risk of rebound hyperbilirubinemia (return of total serum bilirubin to phototherapy threshold within 72 hours) after discontinuation of inpatient phototherapy in neonates >= 35 weeks gestation. The score uses gestational age, age at phototherapy initiation, and the difference between the AAP phototherapy threshold and the TSB level at termination.

Usage

rebound_hyperbilirubinemia_score(gestational_age_weeks, age_initiation_hours,
                                 tsb_termination_mg_dl, aap_threshold_mg_dl)

Value

A list containing:

Rebound_Score

The calculated risk score.

Rebound_Risk_Probability

Estimated probability of rebound hyperbilirubinemia.

Arguments

gestational_age_weeks

Numeric. Gestational age in weeks (Must be >= 35).

age_initiation_hours

Numeric. Postnatal age in hours at the time phototherapy was initiated.

tsb_termination_mg_dl

Numeric. Total Serum Bilirubin level (mg/dL) at the time of phototherapy discontinuation.

aap_threshold_mg_dl

Numeric. The AAP phototherapy treatment threshold (mg/dL) for the infant at the time of discontinuation.

References

Chang PW, Kuzniewicz MW, McCulloch CE, Newman TB. A Clinical Prediction Rule for Rebound Hyperbilirubinemia Following Inpatient Phototherapy. Pediatrics. 2017;139(3):e20162896. doi:10.1542/peds.2016-2896

Examples

# Example 1: Low Risk
# 39 weeks, Started at 48 hours, TSB 12, Threshold 16 (Diff 4)
# Score = 0 - 7(2) - 4(4) + 50 = -14 - 16 + 50 = 20
rebound_hyperbilirubinemia_score(39, 48, 12, 16)

# Example 2: High Risk
# 36 weeks (<38), Started at 24 hours, TSB 13, Threshold 14 (Diff 1)
# Score = 15 - 7(1) - 4(1) + 50 = 15 - 7 - 4 + 50 = 54
rebound_hyperbilirubinemia_score(36, 24, 13, 14)