cliot (version 1.0.0)

reids_colposcopic_index: Reid's Colposcopic Index (RCI)

Description

Calculates the Reid's Colposcopic Index (RCI) score to grade the severity of premalignant cervical lesions during colposcopy. The score is based on four colposcopic signs: lesion margin, color of acetowhitening, vascular patterns, and iodine staining response.

Usage

reids_colposcopic_index(lesion_margin, acetowhitening_color, vascular_patterns,
                        iodine_staining)

Value

A list containing:

RCI_Score

The calculated total score (Range 0-8).

Predicted_Histology

Predicted histologic grade (Low, Intermediate, or High grade).

Arguments

lesion_margin

Numeric (0-2). Characteristics of the lesion margin. 0: Condylomatous or micropapillary contour; indistinct, flocculated, or feathered margins; jagged/angular lesions; satellite lesions beyond the transformation zone. 1: Regular lesions with smooth, straight outlines. 2: Rolled, peeling edges; internal borders between areas of differing appearance.

acetowhitening_color

Numeric (0-2). Color of the lesion after acetic acid application. 0: Shiny, snow-white; indistinct acetowhitening; semitransparent. 1: Shiny, off-white; intermediate white; gray-white. 2: Dull, oyster gray; dense/opaque acetowhitening.

vascular_patterns

Numeric (0-2). Characteristics of blood vessels within the lesion. 0: Uniform, fine-caliber vessels; poorly formed patterns; nondilated capillary loops. 1: Absence of surface vessels after acetic acid soaking. 2: Definite, coarse punctation or mosaicism; dilated vessels arranged in well-defined patterns.

iodine_staining

Numeric (0-2). Response to Lugol's iodine solution. 0: Positive iodine uptake (mahogany brown); or negative uptake (mustard yellow) in a lesion scoring <=2 points on the first three criteria. 1: Partial iodine uptake; variegated/tortoise-shell appearance. 2: Negative iodine uptake (mustard yellow) in a lesion scoring >=3 points on the first three criteria.

References

Reid R, Scalzi P. Genital warts and cervical cancer. VII. An improved colposcopic index for differentiating benign papillomaviral infections from high-grade cervical intraepithelial neoplasia. Am J Obstet Gynecol. 1985;153(6):611-618. doi:10.1016/0002-9378(85)90245-2

Examples

# Example 1: High Grade Lesion
# Rolled edges (2), Dull gray (2), Coarse mosaic (2), Negative iodine (2)
# Score = 8
reids_colposcopic_index(2, 2, 2, 2)

# Example 2: Low Grade Lesion
# Irregular margin (0), Snow white (0), Fine vessels (0), Positive iodine (0)
# Score = 0
reids_colposcopic_index(0, 0, 0, 0)