cliot (version 1.0.0)

resect90_lung_mortality_score: RESECT-90 Score for Lung Resection Mortality

Description

Calculates the RESECT-90 score to estimate the 90-day risk of mortality in patients undergoing lung resection (e.g., lobectomy, pneumonectomy). The model is a multivariable logistic regression derived from a large UK cohort (Taylor et al., 2021). It incorporates patient demographics, comorbidities, and surgical factors.

Usage

resect90_lung_mortality_score(age, sex, ecog_ps, dlco_percent, bmi, creatinine,
                              anemia, arrhythmia, right_sided_resection,
                              thoracotomy_approach, malignant_diagnosis,
                              num_resected_segments, creatinine_units = "mg/dL")

Value

A list containing:

RESECT90_Score_Percent

The estimated percentage probability of death within 90 days of surgery.

Interpretation

Brief context for the result.

Arguments

age

Numeric. Patient age in years.

sex

String. "Male" or "Female". (Male sex is associated with higher risk).

ecog_ps

Numeric. Eastern Cooperative Oncology Group (ECOG) performance status (0-4).

dlco_percent

Numeric. Percentage predicted diffusion capacity of the lung for carbon monoxide (DLCO).

bmi

Numeric. Body Mass Index in kg/m^2. (Higher BMI is associated with lower risk in this model).

creatinine

Numeric. Serum creatinine level.

anemia

Numeric (0 or 1). Presence of preoperative anemia. (1 = Yes).

arrhythmia

Numeric (0 or 1). History of preoperative arrhythmia (e.g., Atrial Fibrillation). (1 = Yes).

right_sided_resection

Numeric (0 or 1). Is the surgery a right-sided resection? (1 = Yes).

thoracotomy_approach

Numeric (0 or 1). Is the surgery performed via open thoracotomy (vs VATS/Robotic)? (1 = Yes).

malignant_diagnosis

Numeric (0 or 1). Is the resection for a malignant diagnosis? (1 = Yes).

num_resected_segments

Numeric. Number of bronchopulmonary segments resected (e.g., Lobectomy ~3-5, Pneumonectomy ~10).

creatinine_units

String. Units for creatinine. "mg/dL" (default) or "umol/L".

References

Taylor M, et al. Development and internal validation of a clinical prediction model for 90-day mortality after lung resection: the RESECT-90 score. Interact Cardiovasc Thorac Surg. 2021.

Examples

resect90_lung_mortality_score(
  age = 70,
  sex = "male",
  ecog_ps = 1,
  dlco_percent = 60,
  bmi = 25,
  creatinine = 1.0,
  anemia = 0,
  arrhythmia = 0,
  right_sided_resection = 1,
  thoracotomy_approach = 1,
  malignant_diagnosis = 1,
  num_resected_segments = 3
)