cliot (version 1.0.0)

rome_iv_functional_biliary_sod: Rome IV Diagnostic Criteria for Functional Biliary Sphincter of Oddi Disorder (SOD)

Description

Evaluates the Rome IV diagnostic criteria for Functional Biliary Sphincter of Oddi Disorder (SOD), which is characterized by recurrent episodes of biliary pain in the absence of structural or metabolic explanations. The diagnosis is based on a set of general criteria, with manometry used for subtype classification.

Usage

rome_iv_functional_biliary_sod(episode_pain, other_pain_excluded,
                               normal_liver_enzymes, normal_pancreatic_enzymes,
                               normal_imaging, not_explained_by_other_condition,
                               manometry_normal_or_high)

Value

A list containing:

Diagnosis

The diagnostic result, including subtype based on presumed manometry results (Type I/II if positive manometry, Type III if negative/manometry not done).

Arguments

episode_pain

Numeric (0 or 1). Presence of recurrent episodes of biliary pain (pain in the epigastrium and/or right upper quadrant, meeting specific characteristics). (1 = Yes).

other_pain_excluded

Numeric (0 or 1). Have other causes of abdominal pain been excluded? (1 = Yes).

normal_liver_enzymes

Numeric (0 or 1). Is there documentation of normal liver enzymes (ALT/AST, ALP) and bilirubin? (1 = Yes).

normal_pancreatic_enzymes

Numeric (0 or 1). Is there documentation of normal pancreatic enzymes (amylase/lipase)? (1 = Yes).

normal_imaging

Numeric (0 or 1). Is there documentation of normal transabdominal ultrasound or Endoscopic Ultrasound (EUS) with no structural abnormalities? (1 = Yes).

not_explained_by_other_condition

Numeric (0 or 1). Are symptoms NOT fully explained by another medical condition (e.g., celiac disease, peptic ulcer)? (1 = Yes).

manometry_normal_or_high

Numeric (0 or 1). Does Sphincter of Oddi manometry show elevated basal pressure or a normal pressure (used for subtyping)? (1 = Yes, pressure is high or normal).

References

Corazziari E, Shaffer EA, Hogan WJ, et al. Functional Disorders of the Gallbladder and Sphincter of Oddi. Gastroenterology. 2016;150:1443-1455. doi:10.1053/j.gastro.2016.02.044

Examples

# Example 1: Type I/II SOD (General criteria met + positive manometry)
rome_iv_functional_biliary_sod(1, 1, 1, 1, 1, 1, 1)

# Example 2: Type III SOD (General criteria met + negative/unknown manometry)
rome_iv_functional_biliary_sod(1, 1, 1, 1, 1, 1, 0)