cliot (version 1.0.0)

rome_iv_functional_gallbladder_disorder: Rome IV Diagnostic Criteria for Functional Gallbladder Disorder

Description

Evaluates the Rome IV diagnostic criteria for Functional Gallbladder Disorder (FGD), a functional biliary disorder characterized by pain of presumed biliary origin in the absence of gallstones or structural abnormality, and objective evidence of impaired gallbladder motility.

Usage

rome_iv_functional_gallbladder_disorder(biliary_pain, normal_liver_enzymes,
                                        normal_pancreatic_enzymes, normal_imaging,
                                        low_ejection_fraction,
                                        not_explained_by_other_condition,
                                        symptom_onset_ge_6_months,
                                        symptoms_active_last_3_months)

Value

A list containing:

Diagnosis

"Criteria Met for Functional Gallbladder Disorder" or "Criteria Not Met".

Arguments

biliary_pain

Numeric (0 or 1). Presence of recurrent episodes of biliary pain (pain in the epigastrium and/or right upper quadrant). (1 = Yes).

normal_liver_enzymes

Numeric (0 or 1). Is there documentation of normal liver enzymes (ALT/AST, ALP) and conjugated bilirubin? (1 = Yes).

normal_pancreatic_enzymes

Numeric (0 or 1). Is there documentation of normal pancreatic enzymes (amylase/lipase)? (1 = Yes).

normal_imaging

Numeric (0 or 1). Is there documentation of no gallstones or other structural pathology on transabdominal ultrasound? (1 = Yes).

low_ejection_fraction

Numeric (0 or 1). Is the gallbladder ejection fraction low (<38% or site-specific abnormal cutoff) on cholecystokinin-stimulated scintigraphy (HIDA scan)? (1 = Yes).

not_explained_by_other_condition

Numeric (0 or 1). Are symptoms NOT fully explained by another medical condition (e.g., peptic ulcer disease, GERD, coronary artery disease)? (1 = Yes).

symptom_onset_ge_6_months

Numeric (0 or 1). Did symptom onset occur at least 6 months prior to diagnosis? (1 = Yes).

symptoms_active_last_3_months

Numeric (0 or 1). Have symptoms been active for the last 3 months? (1 = Yes).

References

Corazziari E, Shaffer EA, Hogan WJ, et al. Functional Disorders of the Gallbladder and Sphincter of Oddi. Gastroenterology. 2016;150:1443-1455. doi:10.1053/j.gastro.2016.02.044

Examples

# Example 1: Diagnosis Met
# All organic causes excluded, typical pain, and low EF documented
rome_iv_functional_gallbladder_disorder(1, 1, 1, 1, 1, 1, 1, 1)

# Example 2: Not Met (EF normal)
# All structural/lab criteria met, but EF is normal (0)
rome_iv_functional_gallbladder_disorder(1, 1, 1, 1, 0, 1, 1, 1)