cliot (version 1.0.0)

travis_uc_criteria: Travis Criteria (Oxford Criteria) for Ulcerative Colitis

Description

Calculates the Travis (Oxford) Criteria to predict the failure of intravenous corticosteroid therapy in patients with severe ulcerative colitis. The assessment is performed on Day 3 of treatment. Patients meeting the criteria have a significantly higher risk (approximately 85%) of requiring colectomy.

Usage

travis_uc_criteria(stool_frequency_day3, crp_day3)

Value

A list containing:

Result

Interpretation of the risk (High vs. Lower).

Predicted_Colectomy_Rate

Estimated probability of requiring colectomy.

Arguments

stool_frequency_day3

Numeric. The number of stools passed on Day 3 of IV steroid treatment.

crp_day3

Numeric. The C-reactive protein level (mg/L) on Day 3 of IV steroid treatment.

Details

The criteria for predicting a high risk of colectomy are:

• Stool frequency > 8 times/day OR

• Stool frequency > 3 times/day AND CRP > 45 mg/L

References

Travis SP, Farrant JM, Ricketts C, et al. Predicting outcome in severe ulcerative colitis. Gut. 1996;38(6):905-910. doi:10.1136/gut.38.6.905

Examples

# Example 1: High Risk (Frequency > 8)
# 9 stools, CRP 10
travis_uc_criteria(9, 10)

# Example 2: High Risk (Frequency > 3 and CRP > 45)
# 4 stools, CRP 50
travis_uc_criteria(4, 50)

# Example 3: Lower Risk
# 3 stools, CRP 60 (Frequency not > 3)
travis_uc_criteria(3, 60)