ucsf_capra_score: UCSF CAPRA Score for Prostate Cancer Risk

Description

Calculates the UCSF CAPRA (Cancer of the Prostate Risk Assessment) Score to predict pathological outcomes and recurrence-free survival after radical prostatectomy. The score utilizes preoperative PSA, Gleason score, clinical T stage, percent positive biopsy cores, and age.

Usage

ucsf_capra_score(psa, gleason_primary, gleason_secondary, clinical_t_stage,
                 percent_positive_cores, age)

Value

A list containing:

CAPRA_Score: The calculated total score (Range 0-10).
Risk_Category: Risk classification (Low: 0-2, Intermediate: 3-5, High: 6-10).
Est_5_Year_Recurrence_Free_Survival: Estimated percentage of patients recurrence-free at 5 years post-prostatectomy.

Arguments

psa: Numeric. Preoperative PSA level in ng/mL.
gleason_primary: Numeric. The primary Gleason pattern (1-5).
gleason_secondary: Numeric. The secondary Gleason pattern (1-5).
clinical_t_stage: String. Clinical T stage. "t1" or "t2": 0 points. "t3a": 1 point.
percent_positive_cores: Numeric. Percentage of biopsy cores positive for cancer (0-100).
age: Numeric. Patient age in years.

References

Cooperberg MR, Pasta DJ, Elkin EP, et al. The University of California, San Francisco Cancer of the Prostate Risk Assessment score: a straightforward and reliable preoperative predictor of disease recurrence after radical prostatectomy. J Urol. 2005;173(6):1938-1942. doi:10.1097/01.ju.0000158155.33890.e7

Examples

Run this code


# Example 1: Low Risk
# PSA 5, Gleason 3+3, T1c, 20% cores, Age 45
# Score = 0
ucsf_capra_score(5, 3, 3, "t1", 20, 45)

# Example 2: High Risk
# PSA 25, Gleason 4+3, T3a, 50% cores, Age 65
# Score = 3(PSA) + 3(Gleason) + 1(Stage) + 1(Cores) + 1(Age) = 9
ucsf_capra_score(25, 4, 3, "t3a", 50, 65)

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