rescale.vaf

<p>clonal structure data frame as output of enumerate.clones</p>

<p>Rescale VAF of subclones such that their total VAF must not
exceed their parent clone VAF. When infered using bootstrap test, sometime
the estimated total mean/median VAFs of subclones &gt; VAF of parent clones
which makes drawing difficult (ie. subclone receive wider polygon than parent
clone. This function rescale the VAF of the subclone for drawing purpose
only, not for the VAF estimate.</p>

clonevol performs clonal ordering and visualization using
the variant clustering results. It uses a bootstrap resampling
technique to estimate the cellular prevalence of the clones within
samples and probabilistically model clonal ordering constraints
(sum and cross rules), hence it tolerates error and variability
in cellular prevalence estimates of individual variants.

Ha X. Dang

rescale.vaf: Rescale VAF of subclones for visualzation purpose

Description

Usage

Arguments