map_mask

Internal helper function for finemap.signals

Performs the colocalisation tests described in
Giambartolomei et al (2013) <doi:10.1371/journal.pgen.1004383>,
Wallace (2020) <doi:10.1371/journal.pgen.1008720>,
Wallace (2021) <doi:10.1371/journal.pgen.1009440>.

Chris Wallace

coloc

Colocalisation Tests of Two Genetic Traits

Claudia Giambartolomei

Vincent Plagnol

map_mask function

<dl><dt>D</dt>
<dd>dataset in standard coloc format</dd>
<dt>LD</dt>
<dd>named matrix of r</dd>
<dt>r2thr</dt>
<dd>mask all snps with r2 &gt; r2thr with any in sigsnps</dd>
<dt>sigsnps</dt>
<dd>names of snps to mask</dd></dl>

Arguments

Author

find the next most significant SNP, masking a list of sigsnps — map_mask

<dl>

<dt>D</dt>
<dd>dataset in standard coloc format</dd>


<dt>LD</dt>
<dd>named matrix of r</dd>


<dt>r2thr</dt>
<dd>mask all snps with r2 &gt; r2thr with any in sigsnps</dd>


<dt>sigsnps</dt>
<dd>names of snps to mask</dd>

</dl>

map_mask: find the next most significant SNP, masking a list of sigsnps

Description

Usage

Value

Arguments

Author