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compound.Cox (version 3.31)

Univariate Feature Selection and Compound Covariate for Predicting Survival, Including Copula-Based Analyses for Dependent Censoring

Description

Univariate feature selection and compound covariate methods under the Cox model with high-dimensional features (e.g., gene expressions). Available are survival data for non-small-cell lung cancer patients with gene expressions (Chen et al 2007 New Engl J Med) , statistical methods in Emura et al (2012 PLoS ONE) , Emura & Chen (2016 Stat Methods Med Res) , and Emura et al (2019). Algorithms for generating correlated gene expressions are also available. Estimation of survival functions via copula-graphic (CG) estimators is also implemented, which is useful for sensitivity analyses under dependent censoring (Yeh et al 2023 Biomedicines) and factorial survival analyses (Emura et al 2024 Stat Methods Med Res) .

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Version

Install

install.packages('compound.Cox')

Monthly Downloads

798

Version

3.31

License

GPL-2

Maintainer

Takeshi Emura

Last Published

October 5th, 2024

Functions in compound.Cox (3.31)

CG.Clayton

Copula-graphic estimator under the Clayton copula.
X.tag

Generate a matrix of gene expressions in the presence of tag genes
uni.Wald

Univariate Cox Wald test
dependCox.reg

Univariate Cox regression under dependent censoring.
CG.Frank

Copula-graphic estimator under the Frank copula.
uni.score

Univariate Cox score test
surv.factorial

Factorial survival analysis under dependent censoring
compound.reg

Compound shrinkage estimation under the Cox model
dependCox.reg.CV

Cox regression under dependent censoring.
cindex.CV

Cross-validated c-index for measuring the predictive accuracy of a prognostic index under a copula-based dependent censoring model.
compound.Cox-package

Univariate Feature Selection and Compound Covariate for Predicting Survival, Including Copula-Based Analyses for Dependent Censoring
uni.selection

Univariate feature selection based on univariate significance tests
CG.Gumbel

Copula-graphic estimator under the Gumbel copula.
Lung

Survival data for patients with non-small-cell lung cancer.
X.pathway

Generate a matrix of gene expressions in the presence of gene pathways
PBC

Primary biliary cirrhosis (PBC) of the liver data
CG.test

Testing survival difference of two groups via the CG estimators