confidenceSim (version 0.1.0)

getConfidenceFromBounds: Get Confidence Levels from Group Sequential Bounds

Description

Derive confidence-based decision thresholds for efficacy and inferiority from a group sequential design.

Usage

getConfidenceFromBounds(design)

Value

List of values:

• critical.values: Critical z-levels at each stage

• alpha.spending.one.sided: One-sided alpha critical values for each stage

• alpha.spending.cumulative: One-sided alpha accumulated by each stage

• confidence.threshold.efficacy: Upper bounds for confidence i.e. declare efficacy if exceeded

• confidence.threshold.inferiority: Lower bounds for confidence i.e. declare inferiority if below

Arguments

design

TrialDesign object generated from 'getGSDesign'.

See Also

getGSDesign()

Examples

# confidence bounds for a 6-stage trial with a maximum sample size of 1000
bounds <- getConfidenceFromBounds(getGSDesign(looks=seq(500, 1000, 100)))