logd_alpha

A Bayesian method for Phenome-wide association studies (PheWAS) that identifies causal associations between genetic variants and traits, while simultaneously addressing confounding due to linkage disequilibrium. For details see
Manipur et al (2024, Nature Communications) <doi:10.1038/s41467-024-49990-8>.

Ichcha Manipur

cophescan

Adaptation of the Coloc Method for PheWAS

Chris Wallace

logd_alpha function

<dl><dt>a</dt>
<dd>current alpha</dd>
<dt>alpha_mean</dt>
<dd>prior for the mean of alpha</dd>
<dt>alpha_sd</dt>
<dd>prior for the standard deviation of alpha</dd></dl>

Arguments

dnorm for alpha — logd_alpha

<dl>

<dt>a</dt>
<dd>current alpha</dd>


<dt>alpha_mean</dt>
<dd>prior for the mean of alpha</dd>


<dt>alpha_sd</dt>
<dd>prior for the standard deviation of alpha</dd>

</dl>

logd_alpha: dnorm for alpha

Description

Usage

Value

Arguments