coxme (version 2.2-1)

coxmeMlist: Coxme variance function

Description

This variance function accepts a list of matrices, which define a correlation structure for a coxme fit.

Usage

coxmeMlist(varlist, rescale = TRUE, pdcheck = TRUE, positive = TRUE)

Arguments

varlist
a list containing one or more matrix or bdsmatrix objects.
rescale
if TRUE, each input matrix is rescaled to have a diagonal of 1. (Kinship matrices for instance are often generated with a diagonal of .5 and would be multiplied by 2).
pdcheck
check each matrix to ensure that it is positive definite
positive
constrain coefficients to be positive. This may also be a vector of the same length as varlist

Value

  • a coxme variance family object, used by coxme in the fitting process.

Details

If two matrices $A$ and $B$ were given, this fits the variance structure $V= \sigma_1^2 A + \sigma_2^2 B$, where the variances $\sigma_1^2$ and $\sigma_2^2$ are parameters that will be optimized by coxme, treating $A$ and $B$ as fixed.

See Also

coxme