coxme v2.2-14

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by Terry Therneau View Source

Mixed Effects Cox Models

This package fits Cox proportional hazards models containing both fixed and random effects. The random effects can have a general form, of which familial interactions (a "kinship" matrix) is a particular special case. Note that the simplest case of a mixed effects Cox model, i.e. a single random per-group intercept, is also called a "frailty" model. The approach is based on Rippatti and Palgren, Biometrics 2002.

Functions in coxme

Name	Description
print.lmekin	Print function for lmekin
lmekin.object	lmekin object
coxme.control	Auxillary parameters for controlling coxme fits.
logLik.coxme	The logLik method for coxme objects
print.coxme	Print method for a coxme fit.
predict.coxme	Predictions for a coxme object.
lmekin	Fit a linear mixed effects model
lmekin.control	Auxillary parameters for controlling lmekin fits.
fixef.lmekin	Extraction functions for Lmekin
fixef.coxme	Extraction functions for Coxme
ranef	Import from package nlme
coxme	Fit a mixed effects Cox model
coxmeFull	Variance family function for coxme fits.
coxmeMlist	Coxme variance function
VarCorr	Import from package nlme
expand.nested	Expand nested factors
eortc	Simulated data set based on an EORTC trial
coxme.object	Coxme regression output object
anova.coxme	Analysis of Deviance for a Cox model.
fixed.effects	Import from package nlme
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Vignettes of coxme

Name
figures/lung3.pdf
coxme.Rnw
gaw.rda
laplace.Rnw
lmekin.Rnw
variance.Rnw
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Details

Priority	optional
LinkingTo	bdsmatrix
LazyData	Yes
LazyLoad	Yes
License	LGPL-2
NeedsCompilation	yes
Packaged	2019-07-03 17:31:43 UTC; therneau
Repository	CRAN
Date/Publication	2019-07-04 05:10:05 UTC

depends	bdsmatrix (>= 1.3) , methods , R (>= 2.10) , survival (>= 2.36.14)
suggests	kinship2 , mvtnorm
imports	Matrix (>= 1.0) , nlme
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