Provides a comprehensive framework for time series omics analysis, integrating changepoint detection, smooth and shape-constrained trends, and uncertainty quantification. It supports gene- and transcript-level inferences, p-value aggregation for improved power, and both case-only and case-control designs. It includes an interactive 'shiny' interface. The methods are described in Yates et al. (2024) tools:::Rd_expr_doi("10.1101/2024.12.22.630003").
Maintainer: Luke Yates luke.yates@utas.edu.au (ORCID) [copyright holder]
Authors:
Michael Charleston
Jazmine Humphreys
Steven Smith
Useful links: