cpk (version 1.2)

css.fn: Calculates css

Description

Calculates css (steady-state) drug concentration in ug/L, which is the same as ng/ml.

Usage

css.fn(f, dpo, di, cl, wtkg = 86)

Arguments

f

is bioavailability.

dpo

is oral dose administered in ug.

di

is the dosing interval in h.

cl

is the total clearance rate in L/kg/h.

wtkg

is patient weight in kg.

Value

• Returns css in ug/L

References

See cpk-package help.

Examples

f <- 0.74; dpo <- 3440; di <- 4; cl <- 0.37;
css <-css.fn(f, dpo, di, cl)