cpk (version 1.3-1)

bc.ttc.fn: Back-calculation function

Description

Performs a back-calculation to get the target therapeutic concentration (TTC) based on the administered dose.

Usage

bc.ttc.fn(dr, f, cl, wtkg)

Arguments

dr

dr is

f

bioavailability

cl

clearance rate

wtkg

weight in kg average man in US (NHANES III)

Value

Returns the back-calculated TTC (ug/L).

References

See cpk-package help.

Examples

ttc <- 20; dr <- 2.26; cl <- 0.57; f <- 0.74; wtkg <- 86;
dr  <- dr.fn(ttc,cl,wtkg,f)