Design

see <code><a href="/link/?package=crmPack&version=1.0.0" design'="" data-mini-rdoc="crmPack::"></a>'>Design</code>

model

stopping

increments

PLcohortSize

additional arguments for <code><a rd-options="" href="/link/RuleDesign?package=crmPack&version=1.0.0" data-mini-rdoc="crmPack::RuleDesign">RuleDesign</a></code>

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Initialization function for "Design"

methods

Implements a wide range of model-based dose
escalation designs, ranging from classical and modern continual
reassessment methods (CRMs) based on dose-limiting toxicity endpoints to
dual-endpoint designs taking into account a biomarker/efficacy outcome. The
focus is on Bayesian inference, making it very easy to setup a new design
with its own JAGS code. However, it is also possible to implement 3+3
designs for comparison or models with non-Bayesian estimation. The whole
package is written in a modular form in the S4 class system, making it very
flexible for adaptation to new models, escalation or stopping rules.

Giuseppe Palermo

crmPack

Object-Oriented Implementation of CRM Designs

Daniel Sabanes Bove

Wai Yin Yeung

Thomas Jaki

Design function

see <code><a href='<a href='Design'></a>'>Design</a></code>

additional arguments for <code><a rd-options='' href='RuleDesign'>RuleDesign</a></code>

Design: Initialization function for "Design"

Description

Usage

Arguments

Value