DualEndpointRW

see <code><a href="/link/?package=crmPack&version=1.0.0" dualendpointrw'="" data-mini-rdoc="crmPack::"></a>'>DualEndpointRW</code>

sigma2betaW

either &#8220;RW1&#8221; (default) or &#8220;RW2&#8221;, for
specifying the random walk prior on the biomarker level.

smooth

additional parameters, see <code><a href="/link/?package=crmPack&version=1.0.0" dualendpoint'="" data-mini-rdoc="crmPack::"></a>'>DualEndpoint</code>

&#8230;

Initialization function for the "DualEndpointRW" class

methods

Implements a wide range of model-based dose
escalation designs, ranging from classical and modern continual
reassessment methods (CRMs) based on dose-limiting toxicity endpoints to
dual-endpoint designs taking into account a biomarker/efficacy outcome. The
focus is on Bayesian inference, making it very easy to setup a new design
with its own JAGS code. However, it is also possible to implement 3+3
designs for comparison or models with non-Bayesian estimation. The whole
package is written in a modular form in the S4 class system, making it very
flexible for adaptation to new models, escalation or stopping rules.

Giuseppe Palermo

crmPack

Object-Oriented Implementation of CRM Designs

Daniel Sabanes Bove

Wai Yin Yeung

Thomas Jaki

DualEndpointRW function

see <code><a href='<a href='DualEndpointRW'></a>'>DualEndpointRW</a></code>

additional parameters, see <code><a href='<a href='DualEndpoint'></a>'>DualEndpoint</a></code>

DualEndpointRW: Initialization function for the "DualEndpointRW" class

Description

Usage

Arguments

Value