GeneralSimulations-class

.GeneralSimulations

This class captures trial simulations.

classes

Implements a wide range of model-based dose
escalation designs, ranging from classical and modern continual
reassessment methods (CRMs) based on dose-limiting toxicity endpoints to
dual-endpoint designs taking into account a biomarker/efficacy outcome. The
focus is on Bayesian inference, making it very easy to setup a new design
with its own JAGS code. However, it is also possible to implement 3+3
designs for comparison or models with non-Bayesian estimation. The whole
package is written in a modular form in the S4 class system, making it very
flexible for adaptation to new models, escalation or stopping rules.

Giuseppe Palermo

crmPack

Object-Oriented Implementation of CRM Designs

Daniel Sabanes Bove

Wai Yin Yeung

Thomas Jaki

GeneralSimulations-class function

<dl class="dl-horizontal">
<dt><code>data</code></dt><dd>list of produced <code><a href="/link/?package=crmPack&version=1.0.0" data'="" data-mini-rdoc="crmPack::"></a>'>Data</code> objects</dd></dl><dt><code>doses</code></dt><dd>the vector of final dose recommendations</dd><dt><code>seed</code></dt><dd>random generator state before starting the simulation</dd>

Slots

General class for the simulations output — GeneralSimulations-class

General class for the simulations output

GeneralSimulations-class: General class for the simulations output

Description

Arguments

Slots

Details