crmPack-package

crmPack

<p>Object-oriented implementation of CRM designs</p>

package

Implements a wide range of model-based dose
escalation designs, ranging from classical and modern continual
reassessment methods (CRMs) based on dose-limiting toxicity endpoints to
dual-endpoint designs taking into account a biomarker/efficacy outcome. The
focus is on Bayesian inference, making it very easy to setup a new design
with its own JAGS code. However, it is also possible to implement 3+3
designs for comparison or models with non-Bayesian estimation. The whole
package is written in a modular form in the S4 class system, making it very
flexible for adaptation to new models, escalation or stopping rules.

Giuseppe Palermo

Object-Oriented Implementation of CRM Designs

Daniel Sabanes Bove

Wai Yin Yeung

Thomas Jaki

crmPack-package function

Object-oriented implementation of CRM designs — crmPack-package

Object-oriented implementation of CRM designs

crmPack-package: Object-oriented implementation of CRM designs

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