PseudoSimulations

Initialization function of the 'PseudoSimulations' class

methods

Implements a wide range of model-based dose
escalation designs, ranging from classical and modern continual
reassessment methods (CRMs) based on dose-limiting toxicity endpoints to
dual-endpoint designs taking into account a biomarker/efficacy outcome. The
focus is on Bayesian inference, making it very easy to setup a new design
with its own JAGS code. However, it is also possible to implement 3+3
designs for comparison or models with non-Bayesian estimation. The whole
package is written in a modular form in the S4 class system, making it very
flexible for adaptation to new models, escalation or stopping rules.

Daniel Sabanes Bove

crmPack

Object-Oriented Implementation of CRM Designs

Wai Yin Yeung

Giuseppe Palermo

Thomas Jaki

PseudoSimulations function

<dl><dt>fit</dt>
<dd>please refer to <code>PseudoSimulations</code> class object</dd>
<dt>FinalTDtargetDuringTrialEstimates</dt>
<dd>please refer to <code>PseudoSimulations</code> class object</dd>
<dt>FinalTDtargetEndOfTrialEstimates</dt>
<dd>please refer to <code>PseudoSimulations</code> class object</dd>
<dt>FinalTDtargetDuringTrialAtDoseGrid</dt>
<dd>please refer to <code>PseudoSimulations</code> class object</dd>
<dt>FinalTDtargetEndOfTrialAtDoseGrid</dt>
<dd>please refer to <code>PseudoSimulations</code> class object</dd>
<dt>FinalTDEOTCIs</dt>
<dd>please refer to <code>PseudoSimulations</code> class object</dd>
<dt>FinalTDEOTRatios</dt>
<dd>please refer to <code>PseudoSimulations</code> class object</dd>
<dt>FinalCIs</dt>
<dd>please refer to <code>PseudoSimulations</code> class object</dd>
<dt>FinalRatios</dt>
<dd>please refer to <code>PseudoSimulations</code> class object</dd>
<dt>stopReasons</dt>
<dd>please refer to <code>PseudoSimulations</code> class object</dd>
<dt>...</dt>
<dd>additional parameters from <code>GeneralSimulations</code></dd></dl>

Arguments

Initialization function of the 'PseudoSimulations' class — PseudoSimulations

<dl>

<dt>fit</dt>
<dd>please refer to <code>PseudoSimulations</code> class object</dd>


<dt>FinalTDtargetDuringTrialEstimates</dt>
<dd>please refer to <code>PseudoSimulations</code> class object</dd>


<dt>FinalTDtargetEndOfTrialEstimates</dt>
<dd>please refer to <code>PseudoSimulations</code> class object</dd>


<dt>FinalTDtargetDuringTrialAtDoseGrid</dt>
<dd>please refer to <code>PseudoSimulations</code> class object</dd>


<dt>FinalTDtargetEndOfTrialAtDoseGrid</dt>
<dd>please refer to <code>PseudoSimulations</code> class object</dd>


<dt>FinalTDEOTCIs</dt>
<dd>please refer to <code>PseudoSimulations</code> class object</dd>


<dt>FinalTDEOTRatios</dt>
<dd>please refer to <code>PseudoSimulations</code> class object</dd>


<dt>FinalCIs</dt>
<dd>please refer to <code>PseudoSimulations</code> class object</dd>


<dt>FinalRatios</dt>
<dd>please refer to <code>PseudoSimulations</code> class object</dd>


<dt>stopReasons</dt>
<dd>please refer to <code>PseudoSimulations</code> class object</dd>


<dt>...</dt>
<dd>additional parameters from <code>GeneralSimulations</code></dd>

</dl>

PseudoSimulations: Initialization function of the 'PseudoSimulations' class

Description

Usage

Value

Arguments