get_result_list

The function <code>fun</code> can use variables that are visible to itself.
The names of these variables have to be given in the vector <code>vars</code>.

internal

programming

Implements a wide range of dose escalation
designs. The focus is on model-based designs, ranging from classical and
modern continual reassessment methods (CRMs) based on dose-limiting toxicity
endpoints to dual-endpoint designs taking into account a biomarker/efficacy
outcome. Bayesian inference is performed via MCMC sampling in JAGS, and it is easy
to setup a new design with custom JAGS code. However, it is also possible to
implement 3+3 designs for comparison or models with non-Bayesian estimation.
The whole package is written in a modular form in the S4 class system, making it
very flexible for adaptation to new models, escalation or stopping rules.
Further details are presented in
Sabanes Bove et al. (2019) <doi:10.18637/jss.v089.i10>.

Daniel Sabanes Bove

crmPack

Object-Oriented Implementation of Dose Escalation Designs

Wai Yin Yeung

Burak Kuersad Guenhan

Giuseppe Palermo

Thomas Jaki

Jiawen Zhu

Ziwei Liao

Dimitris Kontos

Marlene Schulte-Goebel

Doug Kelkhoff

Oliver Boix

Robert Adams

Clara Beck

John Kirkpatrick

Wojciech Wójciak

Guanya Peng

Prerana Chandratre

F. Hoffmann-La Roche AG 

Merck Healthcare KGaA 

Bayer AG 

RPACT GmbH 

get_result_list function

<dl><dt>fun</dt>
<dd>(<code>function</code>) the simulation function for a single iteration, which takes as
single parameter the iteration index.</dd>
<dt>nsim</dt>
<dd>number of simulations to be conducted.</dd>
<dt>vars</dt>
<dd>names of the variables.</dd>
<dt>parallel</dt>
<dd>should the simulation runs be parallelized across the
clusters of the computer?</dd>
<dt>n_cores</dt>
<dd>how many cores should be used for parallel computing?</dd></dl>

Arguments

Helper Function to Obtain Simulation Results List — get_result_list

<dl>

<dt>fun</dt>
<dd>(<code>function</code>) the simulation function for a single iteration, which takes as
single parameter the iteration index.</dd>


<dt>nsim</dt>
<dd>number of simulations to be conducted.</dd>


<dt>vars</dt>
<dd>names of the variables.</dd>


<dt>parallel</dt>
<dd>should the simulation runs be parallelized across the
clusters of the computer?</dd>


<dt>n_cores</dt>
<dd>how many cores should be used for parallel computing?</dd>

</dl>

Helper Function to Obtain Simulation Results List

get_result_list: Helper Function to Obtain Simulation Results List

Description

Usage

Value

Arguments