h_get_formatted_dosegrid

Format a <code>doseGrid</code> for Printing

internal

Implements a wide range of dose escalation
designs. The focus is on model-based designs, ranging from classical and
modern continual reassessment methods (CRMs) based on dose-limiting toxicity
endpoints to dual-endpoint designs taking into account a biomarker/efficacy
outcome. Bayesian inference is performed via MCMC sampling in JAGS, and it is easy
to setup a new design with custom JAGS code. However, it is also possible to
implement 3+3 designs for comparison or models with non-Bayesian estimation.
The whole package is written in a modular form in the S4 class system, making it
very flexible for adaptation to new models, escalation or stopping rules.
Further details are presented in
Sabanes Bove et al. (2019) <doi:10.18637/jss.v089.i10>.

Daniel Sabanes Bove

crmPack

Object-Oriented Implementation of Dose Escalation Designs

Wai Yin Yeung

Burak Kuersad Guenhan

Giuseppe Palermo

Thomas Jaki

Jiawen Zhu

Ziwei Liao

Dimitris Kontos

Marlene Schulte-Goebel

Doug Kelkhoff

Oliver Boix

Robert Adams

Clara Beck

John Kirkpatrick

Wojciech Wójciak

Guanya Peng

Prerana Chandratre

F. Hoffmann-La Roche AG 

Merck Healthcare KGaA 

Bayer AG 

RPACT GmbH 

h_get_formatted_dosegrid function

<dl><dt>grid</dt>
<dd>(<code>numeric</code>) the dose grid</dd>
<dt>units</dt>
<dd>(<code>character</code>) The units in which the values in <code>doseGrid</code> are</dd>
<dt>fmt</dt>
<dd>(<code>character</code>) The format used to display values in <code>doseGrid</code>.
If <code>NA</code>, grid values are not pre-formatted</dd>
<dt>...</dt>
<dd>not used at present
measured. Appended to each value in <code>doseGrid</code> when <code>knit_print</code>ed. The
default, <code>NA</code>, omits the units.</dd></dl>

Arguments

Format a doseGrid for Printing — h_get_formatted_dosegrid

<dl>

<dt>grid</dt>
<dd>(<code>numeric</code>) the dose grid</dd>


<dt>units</dt>
<dd>(<code>character</code>) The units in which the values in <code>doseGrid</code> are</dd>


<dt>fmt</dt>
<dd>(<code>character</code>) The format used to display values in <code>doseGrid</code>.
If <code>NA</code>, grid values are not pre-formatted</dd>


<dt>...</dt>
<dd>not used at present
measured. Appended to each value in <code>doseGrid</code> when <code>knit_print</code>ed. The
default, <code>NA</code>, omits the units.</dd>

</dl>

Format a <code>doseGrid</code> for Printing

h_get_formatted_dosegrid: Format a `doseGrid` for Printing

Description

Usage

Value

Arguments