v_model_params

v_model_params_normal

<a href="https://lifecycle.r-lib.org/articles/stages.html#experimental"><img src="figures/lifecycle-experimental.svg?package=crmPack&version=2.0.0" alt="[Experimental]"></a>
These functions are only used internally to validate the format of an object
with model parameters or inherited classes and therefore not exported.

Implements a wide range of dose escalation
designs. The focus is on model-based designs, ranging from classical and
modern continual reassessment methods (CRMs) based on dose-limiting toxicity
endpoints to dual-endpoint designs taking into account a biomarker/efficacy
outcome. Bayesian inference is performed via MCMC sampling in JAGS, and it is easy
to setup a new design with custom JAGS code. However, it is also possible to
implement 3+3 designs for comparison or models with non-Bayesian estimation.
The whole package is written in a modular form in the S4 class system, making it
very flexible for adaptation to new models, escalation or stopping rules.
Further details are presented in
Sabanes Bove et al. (2019) <doi:10.18637/jss.v089.i10>.

Daniel Sabanes Bove

crmPack

Object-Oriented Implementation of Dose Escalation Designs

Wai Yin Yeung

Burak Kuersad Guenhan

Giuseppe Palermo

Thomas Jaki

Jiawen Zhu

Ziwei Liao

Dimitris Kontos

Marlene Schulte-Goebel

Doug Kelkhoff

Oliver Boix

Robert Adams

Clara Beck

John Kirkpatrick

Wojciech Wójciak

Guanya Peng

Prerana Chandratre

F. Hoffmann-La Roche AG 

Merck Healthcare KGaA 

Bayer AG 

RPACT GmbH 

v_model_params function

<dl><dt>object</dt>
<dd>(<code>ModelParamsNormal</code>) multivariate normal parameters object
to validate.</dd></dl>

Arguments

<ul>
<li><code>v_model_params_normal()</code>: a helper function that validates multivariate normal
parameters.</li>
</ul>

Functions

<a href='https://lifecycle.r-lib.org/articles/stages.html#experimental'><img src='figures/lifecycle-experimental.svg' alt='[Experimental]' /></a>
These functions are only used internally to validate the format of an object
with model parameters or inherited classes and therefore not exported.

Internal Helper Functions for Validation of Model Parameters Objects — v_model_params

<dl>

<dt>object</dt>
<dd>(<code>ModelParamsNormal</code>) multivariate normal parameters object
to validate.</dd>

</dl>

Internal Helper Functions for Validation of Model Parameters Objects

v_model_params: Internal Helper Functions for Validation of Model Parameters Objects

Description

Usage

Value

Arguments

Functions