crmPack (version 2.1.0)

h_determine_dlts: Helper function to determine the dlts including first separate and placebo condition

Description

Helper function to determine the dlts including first separate and placebo condition

Usage

h_determine_dlts(
  data,
  dose,
  prob,
  prob_placebo = 0,
  prob_response = 0,
  prob_response_placebo = 0,
  cohort_size,
  cohort_size_placebo = 0,
  dose_grid,
  first_separate
)

Value

updated data object

Arguments

data

(Data)
what data to start from.

dose

(number)
current dose.

prob

(number)
defines the true probability for a DLT at the dose.

prob_placebo

(number)
defines the true probability for a DLT at a placebo condition.

prob_response

(number)
defines the true probability for a response at the dose.

prob_response_placebo

(number)
defines the true probability for a response at a placebo condition.

cohort_size

(number)
the cohort size to use.

cohort_size_placebo

(number)
the cohort size to use for placebo condition.

dose_grid

(numeric)
the dose_grid as specified by the user.

first_separate

(flag)
whether the first patient is enrolled separately.